Pyelonephritis Organism-Specific Therapy
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Organism-specific therapeutic regimens for pyelonephritis are provided below, including those for the following [1, 2, 3] :
See the list below:
Ciprofloxacin 500 mg PO q12 h or
Levofloxacin 500 mg IV q24 h or
Ceftriaxone 1g IV q24 h
See the list below:
Trimethoprim-sulfamethoxazole (160mg/800mg) 1 DS tablet PO q12 h or
Ampicillin 500 mg PO q6 h or 2 g IV q6 h
See the list below:
Trimethoprim-sulfamethoxazole (160/800 mg) 1 DS tablet PO q12 h or
Ampicillin 500 mg PO q6 h or 2 g IV q6h
See the list below:
Ampicillin 500 mg PO q6 h or 2 g IV q6 h or
Ciprofloxacin 500 mg PO q12 h or
Levofloxacin 500 mg IV q24 h or
Ceftriaxone 1 g IV q24 h
See the list below:
Ciprofloxacin 500 mg PO q12 h or
Levofloxacin 500 mg IV q24 h or
Ceftriaxone 1 g IV q24 h
See the list below:
Amoxicillin 875 mg PO q12 h
Gupta K, Hooton TM, Naber KG, et al. International clinical practice guidelines for the treatment of acute uncomplicated cystitis and pyelonephritis in women: A 2010 update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases. Clin Infect Dis. 2011 Mar. 52(5):e103-20. [Medline].
Peco-Antić A, Paripović D, Buljugić S, Kruscić D, Spasojević B, Cvetković M, et al. Antibiotic resistance of uropathogens in newborns and young children with acute pyelonephritis. Srp Arh Celok Lek. 2012 Mar-Apr. 140 (3-4):179-83. [Medline].
Er DK, Dundar D, Uzuner H, Osmani A. Relationship between phylogenetic groups, antibiotic resistance and patient characteristics in terms of adhesin genes in cystitis and pyelonephritis isolates of Escherichia coli. Microb Pathog. 2015 Oct 28. 89:188-194. [Medline].
Mony Fraer, MD, MHCDS, FACP, FASN Associate Professor, Division of Nephrology, Department of Medicine, University of Iowa Hospitals and Clinics; Staff Physician, Iowa City Veterans Affairs Medical Center
Disclosure: Nothing to disclose.
Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference
Disclosure: Received salary from Medscape for employment. for: Medscape.
Thomas E Herchline, MD Professor of Medicine, Wright State University, Boonshoft School of Medicine; Medical Consultant, Public Health, Dayton and Montgomery County (Ohio) Tuberculosis Clinic
Thomas E Herchline, MD is a member of the following medical societies: Alpha Omega Alpha, Infectious Diseases Society of America, Infectious Diseases Society of Ohio
Disclosure: Nothing to disclose.
Kelley Struble, DO Fellow, Department of Infectious Diseases, University of Oklahoma College of Medicine
Kelley Struble, DO is a member of the following medical societies: American College of Physicians and Infectious Diseases Society of America
Disclosure: Nothing to disclose.
Pyelonephritis Organism-Specific Therapy
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