Prolactin
No Results
No Results
processing….
The reference range for prolactin in females is as follows:
Nongravid/nonlactating: 2-29 ng/mL
Gravid: 10-209 ng/mL (third trimester)
The reference range for prolactin in males is 2-18 ng/mL.
Hyperprolactinemia is associated primarily with prolactin-secreting pituitary tumors (prolactinoma).
Conditions associated with prolactin deficiency include anterior pituitary dysfunction secondary to the following:
Postpartum pituitary necrosis (Sheehan syndrome)
Extrapituitary tumor
Treatment of pituitary/extrapituitary tumor
Parasellar disease
Infection (eg, tuberculosis, histoplasmosis)
Infiltrative disease (eg, sarcoidosis, hemochromatosis)
Specifics for collection and panels are as follows:
Specimen type: Blood serum
Container: Vacutainer, red/black top
Collection method: Venipuncture
Specimen volume: 0.6 mL
Other instructions: Collect specimen within 3-4 hours of awakening
Related tests are as follows:
Follicle-stimulating hormone (FSH)
Luteinizing hormone (LH)
Testosterone
Dehydroepiandrosterone (DHEA)
Estrogen
Progesterone
Growth hormone
Prolactin is pituitary hormone that stimulates breast development and milk production in women. Prolactin has no known normal function in men. [1, 2, 3, 4]
An image depicting prolactin can be seen below.
Indications for testing of serum prolactin include the following:
Evaluation of galactorrhea
Evaluation of headache and visual field deficits
Evaluation of pituitary tumors
Evaluation of male and female infertility
Evaluation of amenorrhea/oligomenorrhea
Evaluation of erectile dysfunction
Evaluation of hypogonadism
Monitoring therapy of prolactinoma and detecting recurrences
Hyperprolactinemia may also be associated with the following:
Breast stimulation (transient)
Renal disease
Hyperprolactinemia may also be associated with the following drugs:
Estrogen
Tricyclic antidepressants
Opiates
Amphetamines
Reserpine
Verapamil
Methyldopa
Butyrophenones
H2 blockers
Metoclopramide
Phenothiazines
Risperidone
Segu VB. Prolactinoma. Medscape Drugs & Diseases. Available at http://emedicine.medscape.com/article/124634-overview. November 2, 2015; Accessed: December 11, 2015.
Benson CT. Prolactin Deficiency. Medscape Drugs & Diseases. Available at http://emedicine.medscape.com/article/124526-overview. June 10, 2014; Accessed: December 11, 2015.
Joustra SD, Roelfsema F, Endert E, Ballieux BE, van Trotsenburg AS, Fliers E, et al. Pituitary Hormone Secretion Profiles in IGSF1 Deficiency Syndrome. Neuroendocrinology. 2015 Aug 25. [Medline].
Porta F, Ponzone A, Spada M. Short prolactin profile for monitoring treatment in BH4 deficiency. Eur J Paediatr Neurol. 2015 May. 19 (3):360-3. [Medline].
Anas K Gremida, MD Resident Physician, Combined Internal Medicine-Pediatrics Program, St Louis University School of Medicine
Disclosure: Nothing to disclose.
Thomas M Wheeler, MD Chairman, Department of Pathology and Immunology, WL Moody, Jr, Professor of Pathology, Professor of Urology, Baylor College of Medicine
Thomas M Wheeler, MD is a member of the following medical societies: Alpha Omega Alpha, American Association for Cancer Research, American Medical Association, American Society for Clinical Pathology, American Society of Cytopathology, American Thyroid Association, American Urological Association, College of American Pathologists, United States and Canadian Academy of Pathology, International Society of Urological Pathology, Harris County Medical Society
Disclosure: Received stock from PathXL for medical advisory board. for: PathXL, Inc.
Judy Lin, MD
Disclosure: Nothing to disclose.
Prolactin
Research & References of Prolactin |A&C Accounting And Tax Services
Source